Shedding of the Cell Surface GM-CSF Monocytes: Evidence for Ectodomain of the Soluble GM-CSF Receptor in Human Inflammatory Stimuli Up-Regulate Secretion Colony-Stimulating Factor (GM-CSF) and Granulocyte-Macrophage
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Introduction Genetic background has known to be associated with the outcome of human T cell lymphotropic virus (HTLV) type I infection. In The present study we investigate the association between GM-CSF gene polymorphisms with the outcome of HTLV-I infection. Materials and Methods We analyzed 3 single-nucleotide polymorphisms in the promter region of granulocyte macrophage colony stimulating...
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We have cloned, expressed, and partially purified a naturally occurring, truncated, soluble form of the human granulocyte-macrophage colony-stimulating factor (GM-CSF) receptor alpha subunit to investigate its biochemical and biologic properties. The soluble receptor species lacks the transmembrane and cytoplasmic domains that are presumably removed from the intact receptor cDNA by a mechanism ...
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تاریخ انتشار 2002